The Intercollegiate Men's Lacrosse Coaches Association (IMLCA) revealed its All-Region honors and two USA South Athletic Conference student-athletes from two institutions earned spots on the Region 4 team.

Collecting Honorable Mention honors at attackman was Pfeiffer's Ethan Miles, the 2025 USA South Offensive Player of the Year. Earning Honorable Mention accolades at short stick defensive midfield was Southern Virginia's JT Cutrer.